Functional characterization and receptor binding studies of the malic enzyme thyroid hormone response element.

Article

Functional characterization and receptor binding studies of the malic enzyme thyroid hormone response element.

The Journal of biological chemistry - 15 Jan 1991

Desvergne B, Petty K J, Nikodem V M

Abstract excerpt

We previously showed that the 5'-flanking region of the malic enzyme (ME) gene contains a cis-regulatory element (-281 to -261) that binds thyroid hormone receptors and confers triiodothyronine (T3) inducibility of transcription to the ME promoter (Petty, K.J., Desvergne, B., Mitsuhashi, T., and...

Topics

Animals
Base Sequence
Malate Dehydrogenase
Male
Molecular Sequence Data
Mutation
Plasmids
Promoter Regions, Genetic
Rats
Receptors, Thyroid Hormone
Thyroid Hormones
Transcription, Genetic
Transfection

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