Article
TRPV6 alleles do not influence prostate cancer progression.
BMC cancer - 26 Oct 2009
Kessler Thorsten, Wissenbach Ulrich, Grobholz Rainer, Flockerzi Veit
Abstract excerpt
BACKGROUND: The transient receptor potential, subfamily V, member 6 (TRPV6) is a Ca(2+) selective cation channel. Several studies have shown that TRPV6 transcripts are expressed in locally advanced prostatic adenocarcinoma, metastatic and androgen-insensitive prostatic lesions but are undetectable in healthy prostate tissue and benign prostatic hyperplasia. Two allelic variants of the human trpv6 gene have been...
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