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Article

The chromosome 16q region associated with ankylosing spondylitis includes the candidate gene tumour necrosis factor receptor type 1-associated death domain (TRADD).

Annals of the rheumatic diseases - 1 Jun 2010

Pointon Jennifer J, Harvey David, Karaderi Tugce, Appleton Louise H, Farrar Claire, Stone Millicent A, Sturrock Roger D, Reveille John D, Weisman Michael H, Ward Michael M, Brown Matthew A, Wordsworth B Paul

Abstract excerpt

OBJECTIVE: To replicate and refine the reported association of ankylosing spondylitis (AS) with two non-synonymous single nucleotide polymorphisms (nsSNPs) on chromosome 16q22.1. METHODS: Firstly, 730 independent UK patients with AS were genotyped for rs9939768 and rs6979 and allele frequencies w...

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Share to Case-Control Studies
Share to Chromosomes, Human, Pair 16
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Share to Genetic Predisposition to Disease
Share to Polymorphism, Single Nucleotide
Share to Spondylitis, Ankylosing

Source

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Identifiers

PMID: 19854717
DOI: 10.1136/ard.2009.115147
PMCID: PMC2959172

Genes

TRADD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19854717-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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