Article
Screening for clonal hematopoiesis as a predictive marker for development of therapy-related myeloid neoplasia (t-MN) following neoadjuvant therapy for breast cancer: a Southwest Oncology Group study (S0012).
Breast cancer research and treatment - 1 Jan 2010
Slovak Marilyn L, Bedell Victoria, Lew Danika, Albain Kathy S, Ellis Georgiana K, Livingston Robert B, Martino Silvana, Perez Edith A, Hortobagyi Gabriel N, Sher Dorie, Stock Wendy
Abstract excerpt
A serious complication associated with breast cancer treatment is the increased risk for development of therapy-related myeloid neoplasms (t-MN). To determine whether dose-intensive adjuvant regimens for breast cancer induce genetic damage to hematopoietic stem cells, defined by the emergence of...
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