Article
[Val247Leu polymorphism of beta2 glycoprotein 1 gene may justify the genesis of anti beta2GP1 antibodies and antiphospholipid syndrome in multibacillary leprosy].
Anais brasileiros de dermatologia - 1 Jan 2000
Brochado Maria José Franco, Nascimento Margarida Maria Passeri do, Louzada Junior Paulo, Figueiredo José Fernando C, Roselino Ana Maria
Abstract excerpt
UNLABELLED: BACKGROUND - Multibacillary (MB) leprosy may be manifested with antiphospholipid antibodies (aPL), among which anti-beta2GP1 (beta2-glycoprotein 1). High titers of aPL are associated with APS (Antiphospholipid Syndrome), characterized by thrombosis. The mutation Val247Leu in the domai...
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