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Article

Anti-phospholipid syndrome in seven leprosy patients with thrombotic events on corticosteroid and/or thalidomide regimen: insights on genetic and laboratory profiles.

Revista da Sociedade Brasileira de Medicina Tropical - 1 Jan 2000

Vernal Sebastian, Brochado Maria Jose Franco, Bueno-Filho Roberto, Louzada-Junior Paulo, Roselino Ana Maria

Abstract excerpt

INTRODUCTION: Corticosteroids and/or thalidomides have been associated with thromboembolism events (TBE) in multibacillary (MB) leprosy. This report aimed to determine genetic and laboratory profiles associated with leprosy and TBE. METHODS: Antiphospholipid antibodies (aPL), coagulation-related exams, prothrombin and Leiden's factor V mutations, and ß2-glycoprotein-I (ß2GPI) Val247Leu polymorphism were assessed....

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PMID: 29513853
DOI: 10.1590/0037-8682-0216-2017

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