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Article

Differential association of plasma angiopoietin-like proteins 3 and 4 with lipid and metabolic traits.

Arteriosclerosis, thrombosis, and vascular biology - 1 May 2014

Mehta Nidhi, Qamar Arman, Qu Liming, Qasim Atif N, Mehta Nehal N, Reilly Muredach P, Rader Daniel J

Abstract excerpt

OBJECTIVE: Angiopoietin-like protein 3 (ANGPTL3) and 4 (ANGPTL4) are secreted proteins that inhibit lipoprotein lipase in vitro. Genetic variants at the ANGPTL3 and ANGPTL4 gene loci are significantly associated with plasma lipid traits. The aim of this study was to evaluate the association of plasma ANGPTL3 and ANGPTL4 concentrations with lipid and metabolic traits in a large community-based sample. APPROACH AND...

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Source

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Identifiers

PMID: 24626437
DOI: 10.1161/ATVBAHA.113.302802
PMCID: PMC4104779

Genes

ANGPTL3
ANGPTL4

Provenance

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