Article
Genetic association analysis between TDP-43 polymorphisms and Alzheimer's disease in a Japanese population.
Dementia and geriatric cognitive disorders - 1 Jan 2009
Shibata Nobuto, Ohnuma Tohru, Baba Hajime, Arai Heii
Abstract excerpt
BACKGROUND/AIMS: A recent paper reported that the TAR-DNA binding protein (TDP-43) is the disease protein in amyotrophic lateral sclerosis and frontotemporal lobar dementia with ubiquitin-positive inclusions. In addition, it has been shown that TDP-43 may play a role in the pathogenesis of Alzhei...
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