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Article

Contribution of TARDBP to Alzheimer's disease genetic etiology.

Journal of Alzheimer's disease : JAD - 1 Jan 2010

Brouwers Nathalie, Bettens Karolien, Gijselinck Ilse, Engelborghs Sebastiaan, Pickut Barbara A, Van Miegroet Helen, Montoya Ana Gil, Mattheijssens Maria, Peeters Karin, De Deyn Peter P, Cruts Marc, Sleegers Kristel, Van Broeckhoven Christine

Abstract excerpt

The nuclear transactive response (TAR) DNA binding protein-43, TDP-43, is a major constituent of the ubiquitinated neuronal inclusions in patients with frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS). Missense mutations in TDP-43 have been associated with familial...

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Source

Identifiers

PMID: 20555136
DOI: 10.3233/JAD-2010-100198

Genes

TARDBP

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20555136-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Contribution of TARDBP to Alzheimer's disease genetic etiology.PMID 20555136Read ↗

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