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Article

Characterization of a virulence-associated and cell-wall-located DNase of Streptococcus pyogenes

3 Nov 2009

Abstract excerpt

We investigated culture supernatant proteins from the M1 serotype of Streptococcus pyogenes by two-dimensional gel electrophoresis and peptide mass mapping analysis, and characterized the single protein spots. Among them, we analysed the Spy0747 protein. This protein is homologous to the SsnA protein, a cell-wall-located DNase expressed in Streptococcus suis serotype 2. We designated the Spy0747 protein as SpnA....

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PMID: 19850619
DOI: 10.1099/mic.0.031955-0

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