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Article

Simultaneous transcription of duplicated var2csa gene copies in individual Plasmodium falciparum parasites.

Genome biology - 1 Jan 2009

Brolin Kim J M, Ribacke Ulf, Nilsson Sandra, Ankarklev Johan, Moll Kirsten, Wahlgren Mats, Chen Qijun

Abstract excerpt

BACKGROUND: Single nucleotide polymorphisms are common in duplicated genes, causing functional preservation, alteration or silencing. The Plasmodium falciparum genes var2csa and Pf332 are duplicated in the haploid genome of the HB3 parasite line. Whereas the molecular function of Pf332 remains to be elucidated, VAR2CSA is known to be the main adhesin in placental parasite sequestration. Sequence variations...

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Identifiers

PMID: 19849836
DOI: 10.1186/gb-2009-10-10-r117
PMCID: PMC2784332

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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