Article
Mitochondrial function and insulin resistance in overweight and normal-weight children.
The Journal of clinical endocrinology and metabolism - 1 Dec 2009
Fleischman Amy, Kron Matthew, Systrom David M, Hrovat Mirko, Grinspoon Steven K
Abstract excerpt
BACKGROUND: Obesity has become an epidemic in children, associated with an increase in insulin resistance and metabolic dysfunction. Mitochondrial function is known to be an important determinant of glucose metabolism in adults. However, little is known about the relationship between mitochondrial function and obesity, insulin resistance, energy expenditure, and pubertal development in children. METHODS:...
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