Article
Mitochondrial energy production correlates with the age-related BMI.
Pediatric research - 1 Jan 2009
Wortmann Saskia B, Zweers-van Essen Heidi, Rodenburg Richard J T, van den Heuvel Lambert P, de Vries Maaike C, Rasmussen-Conrad Ellen, Smeitink Jan A M, Morava Eva
Abstract excerpt
Besides characteristic neurologic and musculoskeletal symptoms, children with mitochondrial dysfunction often present with feeding problems and failure to thrive. Substrate depletion for the respiratory chain has an effect on energy expenditure. Secondary mitochondrial dysfunction has been reported in severe chronic malnutrition. We evaluated the nutritional state, the growth parameters, and the metabolic...
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