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Article

Visual impairment in the absence of dystroglycan.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 21 Oct 2009

Satz Jakob S, Philp Alisdair R, Nguyen Huy, Kusano Hajime, Lee Jane, Turk Rolf, Riker Megan J, Hernández Jasmine, Weiss Robert M, Anderson Michael G, Mullins Robert F, Moore Steven A, Stone Edwin M, Campbell Kevin P

Abstract excerpt

Ocular involvement in muscular dystrophy ranges from structural defects to abnormal electroretinograms. While the mechanisms underlying the abnormal retinal physiology in patients are not understood, it is thought that alpha-dystroglycan extracellular interactions are critical for normal visual function. Here we show that beta-dystroglycan anchors dystrophin and the inward rectifying K(+) channel Kir4.1 at glial...

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Identifiers

PMID: 19846701
DOI: 10.1523/JNEUROSCI.0474-09.2009
PMCID: PMC2965532

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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