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Article

Epidemiologic study on survival of chronic myeloid leukemia and Ph(+) acute lymphoblastic leukemia patients with BCR-ABL T315I mutation.

Blood - 17 Dec 2009

Nicolini Franck E, Mauro Michael J, Martinelli Giovanni, Kim Dong-Wook, Soverini Simona, Müller Martin C, Hochhaus Andreas, Cortes Jorge, Chuah Charles, Dufva Inge H, Apperley Jane F, Yagasaki Fumiharu, Pearson Jay D, Peter Senaka, Sanz Rodriguez Cesar, Preudhomme Claude, Giles Francis, Goldman John M, Zhou Wei

Abstract excerpt

The BCR-ABL T315I mutation represents a major mechanism of resistance to tyrosine kinase inhibitors (TKIs). The objectives of this retrospective observational study were to estimate overall and progression-free survival for chronic myeloid leukemia in chronic-phase (CP), accelerated-phase (AP), or blastic-phase (BP) and Philadelphia chromosome-positive (Ph)(+) acute lymphoblastic leukemia (ALL) patients with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19843886
DOI: 10.1182/blood-2009-04-219410
PMCID: PMC4916939

Genes

BCR

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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