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Destruction of spirochete <i>Borrelia burgdorferi</i> round-body propagules (RBs) by the antibiotic Tigecycline

20 Oct 2009

Abstract excerpt

Persistence of tissue spirochetes of Borrelia burgdorferi as helices and round bodies (RBs) explains many erythema-Lyme disease symptoms. Spirochete RBs (reproductive propagules also called coccoid bodies, globular bodies, spherical bodies, granules, cysts, L-forms, sphaeroplasts, or vesicles) are induced by environmental conditions unfavorable for growth. Viable, they grow, move and reversibly convert into...

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PMID: 19843691
DOI: 10.1073/pnas.0908236106

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