Article
Molecular characterization of chronic myeloproliferative neoplasias in México.
Hematology (Amsterdam, Netherlands) - 1 Oct 2009
Ruiz-Argüelles Guillermo J, Garcés-Eisele Javier, Ortiz-López Rocio, Rivas-Llamas Ramón, Gómez-Almaguer David, Ruiz-Delgado Guillermo J
Abstract excerpt
By using novel molecular markers, it is possible to gain information on both the classification and the pathophysiology of the chronic myeloproliferative neoplasia (MPN). In a group of 36 Mexican mestizo patients with MPN, we studied five molecular markers: The BCR/ABL1 fusion gene, the JAK2 V617F mutation, the JAK2 exon 12 mutations, the MPL W515L mutation and the MPL W515K mutation; 17 patients with essential...
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