Article
The Janus Kinase 2 (JAK2) V617F mutation in hematological malignancies in México.
Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion - 1 Jan 2000
Ruiz-Argüelles Guillermo J, Garcés-Eisele Javier, Reyes-Núñez Virginia, Ruiz-Delgado Guillermo J, Navarro-Vázquez Morelis, González-Carrillo Martha L
Abstract excerpt
A new mutation (V617F) affecting the JAK2 gene has been recently described as acquired in patients with myeloproliferative disorders and other myeloid malignancies. Using an amplification refractory mutation system, we investigated this mutation in 70 Mexican mestizo patients with hematological malignancies: 28 cases of acute lymphoblastic leukemia, 17 cases of Ph1-positive chronic myelogenous leukemia, 8...
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