Article
Comprehensive polymorphism analysis of ABO using allele-specific separation by bead technology and subsequent sequencing.
Vox sanguinis - 1 Apr 2010
Danzer M, Polin H, Stabentheiner S, Hartmann C C, Lennartz K, Gabriel C
Abstract excerpt
The ABO system is the most important blood group system in transfusion and transplantation medicine. Over the last decade ABO genotyping was introduced to complement serological analysis but because of the enormous diversity at the ABO locus, DNA-based typing is highly sophisticated. In some genotype combinations and especially when dealing with hybrid genes, cis/trans linkage analysis is necessary. Therefore, we...
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