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Article

Search for primitive Methanopyrus based on genetic distance between Val- and Ile-tRNA synthetases.

Journal of molecular evolution - 1 Oct 2009

Yu Zhiliang, Takai Ken, Slesarev Alexei, Xue Hong, Wong J Tze-Fei

Abstract excerpt

Since evidence indicates that the Last Universal Common Ancestor (LUCA) was phylogenetically closest to Methanopyrus kandleri among living organisms with elucidated genomes, this study has been directed to a search for the most primitive Methanopyrus lineage. For this purpose, the divergence of valyl-tRNA synthetase (ValRS) and isoleucyl-tRNA synthetase (IleRS) was employed as a measure of primitivity. Comparison...

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PMID: 19841848
DOI: 10.1007/s00239-009-9297-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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