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Article

Drosophila foxo acts in males to cause sexual-dimorphism in tissue-specific p53 life span effects.

Experimental gerontology - 1 Feb 2010

Shen Jie, Tower John

Abstract excerpt

Sex-specific selective pressures are hypothesized to lead to sexually antagonistic gene functions that contribute to phenotypes such as aging and cancer. However, relatively little is known about the identity of such genes and possible mechanisms. Here we report that nervous system-specific over-expression of wild-type p53 in Drosophila caused decreased life span in males and increased life span in females. In...

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Identifiers

PMID: 19840842
DOI: 10.1016/j.exger.2009.10.009
PMCID: PMC2814947

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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