Article
Role of seminiferous tubular development in determining the FSH versus LH responsiveness to GnRH in early sexual maturation.
Neuroendocrinology - 1 Jan 2009
Pitteloud Nelly, Thambundit Apisadaporn, Dwyer Andrew A, Falardeau John L, Plummer Lacey, Caronia Lisa M, Hayes Frances J, Lee Hang, Boepple Paul A, Crowley William F
Abstract excerpt
BACKGROUND: The onset of sexual maturation at puberty is a unique developmental period from a neuroendocrine perspective in that it is characterized by enhanced FSH secretion and FSH responsiveness to exogenous GnRH (vs. LH) from the gonadotrope, yet the mechanism of these dynamics remains unclea...
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