Article
Gap junction hemichannels contribute to the generation of diarrhoea during infectious enteric disease.
Gut - 1 Feb 2010
Guttman Julian Andrew, Lin Ann En-Ju, Li Yuling, Bechberger John, Naus Christian C, Vogl A Wayne, Finlay B Brett
Abstract excerpt
OBJECTIVE: The attaching and effacing (A/E) pathogens enterohaemorrhagic Escherichia coli, enteropathogenic E coli and Citrobacter rodentium colonise intestinal tracts, attach to enterocytes, collapse infected cell microvilli and alter numerous host cell processes during infection. Enterocyte alterations result in numerous small molecules being released from host cells that likely contribute to diarrhoeal...
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