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Article

Novel Characterization of Constipation Phenotypes in ICR Mice Orally Administrated with Polystyrene Microplastics.

International journal of molecular sciences - 29 May 2021

Choi Yun Ju, Park Jun Woo, Kim Ji Eun, Lee Su Jin, Gong Jeong Eun, Jung Young-Suk, Seo Sungbaek, Hwang Dae Youn

Abstract excerpt

Indirect evidence has determined the possibility that microplastics (MP) induce constipation, although direct scientific proof for constipation induction in animals remains unclear. To investigate whether oral administration of polystyrene (PS)-MP causes constipation, an alteration in the constipation parameters and mechanisms was analyzed in ICR mice, treated with 0.5 μm PS-MP for 2 weeks. Significant...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34072552
DOI: 10.3390/ijms22115845
PMCID: PMC8198713

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