Article
The challenge of exploiting ABCG2 in the clinic.
Current pharmaceutical biotechnology - 1 Apr 2011
Robey Robert W, Ierano Caterina, Zhan Zhirong, Bates Susan E
Abstract excerpt
ABCG2, or breast cancer resistance protein (BCRP), is an ATP-binding cassette half transporter that has been shown to transport a wide range of substrates including chemotherapeutics, antivirals, antibiotics and flavonoids. Given its wide range of substrates, much work has been dedicated to devel...
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