Article
Involvement of an alternatively spliced mitochondrial oxodicarboxylate carrier in adipogenesis in 3T3-L1 cells.
Journal of biomedical science - 13 Oct 2009
Niimi Masashi, Tao Lian, Lin Shi-Hua, Yin Jun, Wu Xiaoyun, Fukui Hiroyuki, Kambayashi Junichi, Ye Jianping, Sun Bing
Abstract excerpt
BACKGROUND: Adipogenesis is a complex process that involves many genes/proteins at different stages of differentiation. In order to identify genes critical for adipogenesis, we took a novel approach based on phenotype change of individual cell, to search for genes with regulatory roles in adipogenesis genome-wide in 3T3-L1 cells. METHODS: Lentivirus-based inducible random homologous knockdown was used for the...
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