Article
Association of single nucleotide polymorphisms in pro-inflammatory cytokine and toll-like receptor genes with pediatric hematogenous osteomyelitis.
Genetics and molecular research : GMR - 23 May 2016
Osman A E, Mubasher M, ElSheikh N E, AlHarthi H, AlZahrani M S, Ahmed N, ElGhazali G, Bradley B A, Fadil A-S A
Abstract excerpt
Hematogenous osteomyelitis (HO) is a bone infection wherein bacteria penetrate to the bone through the blood stream. Several single nucleotide polymorphisms (SNPs) have been associated with susceptibility to infectious diseases. In this study, we investigated the contribution of SNPs in interleukin (IL)-1B1 (rs16944), IL1A (rs1800587), IL1B (rs1143634), toll-like receptor (TLR)-2 (rs3804099), TLR4 (rs4986790),...
