Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic mutation of vitamin K-dependent gamma-glutamyl carboxylase domain in patients with calcium oxalate urolithiasis.

Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban - 1 Oct 2009

Qiao Jiankun, Wang Tao, Yang Jun, Liu Jihong, Gong Xiaoxin, Guo Xiaolin, Wang Shaogang, Ye Zhangqun

Abstract excerpt

To investigate the exon mutation of vitamin K-dependent gamma-glutamyl carboxylase (GGCX or VKDC) in patients with calcium oxalate urolithasis, renal cortex and peripheral blood samples were obtained from severe hydronephrosis patients (with or without calculi), and renal tumor patients undergoing nephrectomy. GGCX mutations in all 15 exons were examined in 44 patients with calcium oxalate urolithiasis (COU) by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Carbon-Carbon Ligases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromatography, High Pressure Liquid

Share to GGCX gene

Share to Mutation

Share to Urolithiasis

Source

Identifiers

PMID: 19821094
DOI: 10.1007/s11596-009-0514-5

Genes

GGCX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

Genetic mutation of vitamin K-dependent gamma-glutamyl carboxylase domain in patients with calcium oxalate urolithiasis.PMID 19821094Read ↗

Nutritional effects of gamma-glutamyl carboxylase gene polymorphism on the correlation between the vitamin K status and gamma-carboxylation of osteocalcin in young males.Semantic proximity Read ↗

Late diagnosis of primary hyperoxaluria type 2 in the adult: effect of a novel mutation in GRHPR gene on enzymatic activity and molecular modeling.Semantic proximity Read ↗

High-resolution SNP and haplotype maps of the human gamma-glutamyl carboxylase gene (GGCX) and association study between polymorphisms in GGCX and the warfarin maintenance dose requirement of the Japanese population.Semantic proximity Read ↗

A functional single nucleotide polymorphism in the vitamin-K-dependent gamma-glutamyl carboxylase gene (Arg325Gln) is associated with bone mineral density in elderly Japanese women.Semantic proximity Read ↗

γ-Glutamyl carboxylase mutations differentially affect the biological function of vitamin K-dependent proteins.Semantic proximity Read ↗

Effects of gamma-glutamyl carboxylase gene polymorphism (R325Q) on the association between dietary vitamin K intake and gamma-carboxylation of osteocalcin in young adults.Semantic proximity Read ↗

Structural and functional insights into enzymes of the vitamin K cycle.Semantic proximity Read ↗

Polymorphisms in vitamin K-dependent gamma-carboxylation-related genes influence interindividual variability in plasma protein C and protein S activities in the general population.Semantic proximity Read ↗

Association study of DGKH gene polymorphisms with calcium oxalate stone in Chinese population.Semantic proximity Read ↗

Urokinase gene 3'-UTR T/C polymorphism is associated with urolithiasis.Semantic proximity Read ↗

A polymorphism of matrix Gla protein gene is associated with kidney stones.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.