Article
Spread of herpes simplex virus (HSV) strains SC16, ANG, ANGpath and its glyC minus and GlyE minus mutants in DBA-2 mice.
Acta virologica - 1 Aug 1990
Rajcáni J, Herget U, Kaerner H C
Abstract excerpt
Herpes simplex virus type 1 (HSV-1) strains SC16, ANG, its pathogenic variant ANGpath and the mutants ANG-pathgC18 glycoprotein C (glyC) negative and ANGpathI2-4 (glyE negative) were compared for their ability to spread in DBA-2 mice after peripheral inoculation. Virus infectivity assay in 9 organs at days 2, 3, 4, 5, 6, and 10 post-infection (p.i.) and morphologic examinations (immunofluorescence, PAP staining)...
Topics
- Animals
- Antigens, Viral
- Axons
- Herpes Simplex
- Mice
- Mice, Inbred DBA
- Mutation
- Organ Specificity
- Peripheral Nerves
- Simplexvirus
- Species Specificity
