Article
An unusual defective genotype derived from herpes simplex virus strain ANG.
Intervirology - 1 Jan 2000
Schröder C H, Stegmann B, Lauppe H F, Kaerner H C
Abstract excerpt
A defective genotype of herpes simplex virus strain Angelotti (HSV ANG) accumulates in the course of controlled serial high MOI virus passages representing 50-60% of the total number of mature virions in the seventh of these passages. Defective HSV ANG significantly differs from other defective HSV genotypes described so far: the DNA of the defective particles has the same buoyant density as nondefective DNA. In...
Topics
- Cell Line
- DNA Restriction Enzymes
- DNA, Viral
- Genotype
- Simplexvirus
- Thymidine Kinase
