Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Depression and plasma amyloid beta peptides in the elderly with and without the apolipoprotein E4 allele.

Alzheimer disease and associated disorders - 1 Jan 2000

Sun Xiaoyan, Chiu Chi Chia, Liebson Elizabeth, Crivello Natalia A, Wang Lixia, Claunch Joshua, Folstein Marshal, Rosenberg Irwin, Mwamburi D Mkaya, Peter Inga, Qiu Wei Qiao

Abstract excerpt

Depression associated with low plasma amyloid-beta peptide 42 (Abeta42) leading to a high ratio of Abeta40/Abeta42, a biomarker of Alzheimer disease (AD), may represent a unique depression subtype. The relationship between low plasma Abeta42 in depression and the major risk factor of AD, apolipoprotein E4 (ApoE4), is unknown. With the goal of clarifying this relationship, we analyzed 1060 homebound elders with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Alzheimer Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Amyloid beta-Peptides

Share to Apolipoprotein E4

Share to Cross-Sectional Studies

Share to Depression

Share to Peptide Fragments

Share to Polymerase Chain Reaction

Source

Open in PubMed Open full text

Identifiers

PMID: 19812466
DOI: 10.1097/WAD.0b013e31819cb3ac
PMCID: PMC2919337

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Depression and plasma amyloid beta peptides in the elderly with and without the apolipoprotein E4 allele.PMID 19812466Read ↗

Amyloid-associated depression and ApoE4 allele: longitudinal follow-up for the development of Alzheimer's disease.Semantic proximity Read ↗

Metabolism of amyloid-β protein may be affected in depression.Semantic proximity Read ↗

Depression and dementia in relation to apolipoprotein E polymorphism in a population sample age 75+.Semantic proximity Read ↗

APOE Gene Associated with Dementia-Related Traits, Depression, and Anxiety in the Hispanic Population.Semantic proximity Read ↗

Depression in Alzheimer's disease might be associated with apolipoprotein E epsilon 4 allele frequency in women but not in men.Semantic proximity Read ↗

APOE genotype predicts depression in women with Alzheimer's disease: a retrospective study.Semantic proximity Read ↗

Associations between depression, sleep disturbance, and apolipoprotein E in the development of Alzheimer's disease: dementia.Semantic proximity Read ↗

β-Amyloid, APOE and BDNF Genotype, and Depressive and Anxiety Symptoms in Cognitively Normal Older Women and MenSemantic proximity Read ↗

Depressive symptoms and APOE polymorphisms in an elderly population-based sample.Semantic proximity Read ↗

Apolipoprotein E ε4 genotype and the temporal relationship between depression and dementia.Semantic proximity Read ↗

APOE is associated with age-of-onset, but not cognitive functioning, in late-life depression.Semantic proximity Read ↗

ERβ and ApoE isoforms interact to regulate BDNF–5-HT2A signaling and synaptic function in the female brainSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.