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Article

Evaluation of hepatitis C virus core antigen assays in detecting recombinant viral antigens of various genotypes.

Journal of clinical microbiology - 1 Dec 2009

Saeed Mohsan, Suzuki Ryosuke, Kondo Madoka, Aizaki Hideki, Kato Takanobu, Mizuochi Toshiaki, Wakita Takaji, Watanabe Haruo, Suzuki Tetsuro

Abstract excerpt

A single substitution within the hepatitis C virus core antigen sequence, A48T, which is observed in approximately 30% of individuals infected with genotype 2a virus, reduces the sensitivity of a commonly used chemiluminescence enzyme immunoassay. Quantitation of the antigen is improved by using a distinct anticore antibody with a different epitope.

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Source

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Identifiers

PMID: 19812276
DOI: 10.1128/JCM.01437-09
PMCID: PMC2786616

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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