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Clinical utility of total HCV core antigen quantification: a new indirect marker of HCV replication.

Hepatology (Baltimore, Md.) - 1 Jul 2002

Bouvier-Alias Magali, Patel Keyur, Dahari Harel, Beaucourt Stéphanie, Larderie Patrick, Blatt Lawrence, Hezode Christophe, Picchio Gaston, Dhumeaux Daniel, Neumann Avidan U, McHutchison John G, Pawlotsky Jean-Michel

Abstract excerpt

Hepatitis C virus (HCV) RNA detection, viral load quantification, and HCV genotyping are widely used in clinical practice. Recently, the availability of an anticore antigen (Ag) monoclonal antibody allowed development of an enzyme-linked immunosorbent assay (ELISA) detecting and quantifying total HCV core Ag in peripheral blood of HCV-infected patients. The aims of the present study were to investigate the...

Topics

Biomarkers
Genotype
Hepacivirus
Hepatitis C
Humans
Kinetics
RNA, Viral
Sensitivity and Specificity
Viral Core Proteins
Virus Replication

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12085367
DOI: 10.1053/jhep.2002.34130

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