Article
Detection of HCV core antigen in human serum and plasma with an automated chemiluminescent immunoassay.
Transfusion - 1 Mar 2002
Muerhoff A Scott, Jiang Lily, Shah Dinesh O, Gutierrez Robin A, Patel Jigisha, Garolis Cynthia, Kyrk Charles R, Leckie Gregor, Frank Andrea, Stewart James L, Dawson George J
Abstract excerpt
BACKGROUND: Currently, the detection of HCV infection in blood donors relies on the ability of immunoassays to detect circulating HCV antibodies. However, a significant delay exists between the time of infection and the development of antibodies. This delay (window period) can last up to 70 days. The introduction of NAT for the detection of HCV RNA has reduced this window period dramatically. However, NAT is...
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