Common intragenic and extragenic polymorphisms of blood coagulation factors VIII and IX are different in Chinese and Caucasian populations.

doi:10.1111/j.1399-0004.1990.tb03609.x

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Article

Common intragenic and extragenic polymorphisms of blood coagulation factors VIII and IX are different in Chinese and Caucasian populations.

Clinical genetics - 1 Dec 1990

de la Salle C, Wu Q, Baas M J, Hanauer A, Ruan C, Cazenave J P

Abstract excerpt

In order to examine the possibilities of carrier detection and prenatal diagnosis in hemophilia A and B in the Chinese region of Suzhou, we analyzed four different RFLPs within the factor IX gene and two intragenic RFLPs and one extragenic RFLP for the factor VIII gene. The results obtained show important differences between the Chinese and Caucasian populations. No polymorphism was found within the factor IX...

Topics

Adult
Alleles
China
DNA Probes
Factor IX
Factor VIII
Female
France
Genetic Carrier Screening
Genetic Variation
Genetics, Population
Hemophilia A

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Hemophilia B

Humans

Male

Polymorphism, Genetic

Polymorphism, Restriction Fragment Length

Prenatal Diagnosis

Source

Open in PubMed

Identifiers

PMID: 1981181
DOI: 10.1111/j.1399-0004.1990.tb03609.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1981181-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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