Article
Lack of an association of GNB3 C825T polymorphism and blood pressure in patients with rheumatoid arthritis.
Clinical and experimental hypertension (New York, N.Y. : 1993) - 1 Jul 2009
Panoulas Vasileios F, Smith Jacqueline P, Stavropoulos-Kalinoglou Antonios, Douglas Karen M J, Nightingale Peter, Kitas George D
Abstract excerpt
G-protein beta 3 subunit (GNB3) C825T (rs5443) single nucleotide polymorphism (SNP) has been implicated as a risk factor for essential hypertension in the general population. The effects of this SNP may be more prominent in subjects with endothelial dysfunction (ED). Rheumatoid arthritis (RA) is associated with ED and has a high prevalence of hypertension. Thus far, this SNP has not been studied in RA patients....
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