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Article

Lack of association between the G protein beta3 subunit gene and essential hypertension in Chinese: a case-control and a family-based study.

Journal of molecular medicine (Berlin, Germany) - 1 Nov 2003

Huang Xiaohong, Ju Zhenyu, Song Yan, Zhang Hongye, Sun Kai, Lu Hongyan, Yang Zhiwei, Jose Pedro A, Zhou Gang, Wang Meng, Wang Weifeng, Feng Shixian, Hui Rutai

Abstract excerpt

A C825T polymorphism of the gene encoding the G protein beta3 subunit (GNB3) is associated with enhanced G protein activity and increased intracellular signal transduction. The 825T allele has been implicated in the development of hypertension in some ethnic groups, especially in whites. Studies in Asians and blacks are more controversial, and little information is available on this polymorphism in the...

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Source

Identifiers

PMID: 13679998
DOI: 10.1007/s00109-003-0482-3

Genes

GNB3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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