Article
The HLA-DR beta 16 allogenotype constitutes a risk factor for hypertrophic scarring.
Human immunology - 1 Nov 1990
Castagnoli C, Peruccio D, Stella M, Magliacani G, Mazzola G, Amoroso A, Richiardi P
Abstract excerpt
Nineteen patients that had developed hypertrophic scars subsequent to thermal injury were typed for HLA class II allogenotypes with the restriction fragment length polymorphism technique. A significant association was found with DR beta 16 (pc = 1.45 x 10(-4); relative risk = 12.25). This finding adds evidence to other data suggesting that immunologic phenomena are involved in pathologic scarring. Moreover, the...
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