Article
Association of HLA-DRB1 alleles with keloids in Chinese Han individuals.
Tissue antigens - 1 Oct 2010
Lu W-S, Zhang W-Y, Li Y, Wang Z-X, Zuo X-B, Cai L-Q, Zhu F, Wang J-F, Sun L-D, Zhang X-J, Yang S
Abstract excerpt
Keloids are common abnormal raised fibroproliferative lesions that can occur following even minor cutaneous trauma. There is strong evidence suggesting a genetic susceptibility in individuals affected by keloids including familial heritability, common occurrence in twins, and high prevalence in certain ethnic populations. Human leukocyte antigens (HLAs) have been proposed to modulate the immune response to...
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