Article
Genomic diversity and evolution of Mycobacterium ulcerans revealed by next-generation sequencing.
PLoS pathogens - 1 Sept 2009
Qi Weihong, Käser Michael, Röltgen Katharina, Yeboah-Manu Dorothy, Pluschke Gerd
Abstract excerpt
Mycobacterium ulcerans is the causative agent of Buruli ulcer, the third most common mycobacterial disease after tuberculosis and leprosy. It is an emerging infectious disease that afflicts mainly children and youths in West Africa. Little is known about the evolution and transmission mode of M. ulcerans, partially due to the lack of known genetic polymorphisms among isolates, limiting the application of genetic...
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