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Article

Crystallographic snapshots of iterative substrate translocations during nicotianamine synthesis in Archaea.

Proceedings of the National Academy of Sciences of the United States of America - 22 Sept 2009

Dreyfus Cyril, Lemaire David, Mari Stéphane, Pignol David, Arnoux Pascal

Abstract excerpt

Nicotianamine (NA), a small molecule ubiquitous in plants, is an important divalent metal chelator and the main precursor of phytosiderophores. Nicotianamine synthase (NAS) is the enzyme catalyzing NA synthesis by the condensation of three aminopropyl moieties of S-adenosylmethionine (SAM) and the cyclization of one of them to form an azetidine ring. Here we report five crystal structures of an archaeal NAS from...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19805277
DOI: 10.1073/pnas.0904439106
PMCID: PMC2736904

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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