Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Radiosensitization effect of STI-571 on pancreatic cancer cells in vitro.

International journal of radiation oncology, biology, physics - 1 Nov 2009

Chung Hye Won, Wen Jing, Lim Jong-Baeck, Bang SeungMin, Park Seung Woo, Song Si Young

Abstract excerpt

PURPOSE: To examine STI-571-induced radiosensitivity in human pancreatic cancer cells in vitro. METHODS AND MATERIALS: Three human pancreatic cancer cell lines (Bxpc-3, Capan-1, and MiaPaCa-2) exhibiting different expression levels of c-Kit and platelet-derived growth factor receptor beta (PDGFRbeta) and showing different K-ras mutation types were used. For evaluation of the antitumor activity of STI-571 in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drug Screening Assays, Antitumor
Share to Extracellular Signal-Regulated MAP Kinases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Imatinib Mesylate

Share to Phospholipase C gamma

Share to Radiation-Sensitizing Agents

Share to Receptor, Platelet-Derived Growth Factor beta

Share to Tetrazolium Salts

Share to Thiazoles

Source

Identifiers

PMID: 19801102
DOI: 10.1016/j.ijrobp.2009.06.021

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Radiosensitization effect of STI-571 on pancreatic cancer cells in vitro.PMID 19801102Read ↗

Radiosensitization of the PI3K inhibitor HS-173 through reduction of DNA damage repair in pancreatic cancerSemantic proximity Read ↗

[New perspectives for radiosensitization in pancreatic carcinoma: a review of mechanisms involved in pancreatic tumorigenesis].Semantic proximity Read ↗

Triple Blockade of Oncogenic RAS Signaling Using KRAS and MEK Inhibitors in Combination with Irradiation in Pancreatic Cancer.Semantic proximity Read ↗

Inhibition of RAC1 GTPase sensitizes pancreatic cancer cells to γ-irradiation.Semantic proximity Read ↗

BCN057, a Modulator of GSK3β, Induces KRAS G12D Mutant Pancreatic Cancer Cell DeathSemantic proximity Read ↗

Perspectives on the combination of radiotherapy and targeted therapy with DNA repair inhibitors in the treatment of pancreatic cancerSemantic proximity Read ↗

Radiosensitization of epidermal growth factor receptor/HER2-positive pancreatic cancer is mediated by inhibition of Akt independent of ras mutational status.Semantic proximity Read ↗

PI3K/Akt/mTOR pathway inhibitors enhance radiosensitivity in radioresistant prostate cancer cells through inducing apoptosis, reducing autophagy, suppressing NHEJ and HR repair pathwaysSemantic proximity Read ↗

P53 reactivator PRIMA-1 MET synergizes with 5-Fluorouracil to induce apoptosis in pancreatic tumor cellsSemantic proximity Read ↗

The PI3K/AKT/mTOR signaling pathway inhibitors enhance radiosensitivity in cancer cell linesSemantic proximity Read ↗

Cytotoxicity of combinations of the pan-KRAS SOS1 inhibitor BAY-293 against pancreatic cancer cell linesSemantic proximity Read ↗

Pancreatic stellate cells radioprotect pancreatic cancer cells through β1-integrin signaling.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.