Article
Gene-gene interaction between the low density lipoprotein receptor and apolipoprotein E loci affects lipid levels.
Clinical genetics - 1 Oct 1990
Pedersen J C, Berg K
Abstract excerpt
A restriction fragment length polymorphism (RFLP) at the low density lipoprotein receptor (LDLR) locus, detectable with the restriction enzyme PvuII has been studied in a second series of Norwegian subjects, believed to be representative of the general population. The results confirm the association of normal alleles at the LDLR locus with differences in age- and sex-corrected total and LDL cholesterol. A gene...
Topics
- Adult
- Aged
- Apolipoproteins E
- Cholesterol, LDL
- Chromosome Mapping
- Female
- Gene Frequency
- Genotype
- Humans
- Male
- Middle Aged
- Phenotype
