Article
Normal genetic variation at the low density lipoprotein receptor (LDLR) locus influences cholesterol levels in children.
Clinical genetics - 1 Mar 1993
Poledne R, Pisa Z, Berg K
Abstract excerpt
The population of Czechoslovakia is at high risk of premature atherosclerosis. Normal DNA polymorphism at the low density lipoprotein receptor (LDLR) locus detectable with the restriction enzyme PvuII was analyzed in Czech children with a high or a low concentration of total serum cholesterol. Th...
Topics
- Apolipoproteins B
- Chi-Square Distribution
- Child
- Cholesterol
- Cross-Sectional Studies
- Czechoslovakia
- Female
- Gene Frequency
- Genetic Variation
- Genotype
- Humans
- Hypercholesterolemia
- Lipids
- Male
- Polymorphism, Restriction Fragment Length
- Receptors, LDL
- Triglycerides