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Article

Association of DNA-haplotypes in the human LDL-receptor gene with normal serum cholesterol levels.

Clinical genetics - 1 Dec 1990

Schuster H, Humphries S, Rauh G, Held C, Keller C, Wolfram G, Zöllner N

Abstract excerpt

For the low density lipoprotein receptor (LDLR), many mutations have been characterized which identify this gene as one with an important role in lipid metabolism in patients with familial hypercholesterolemia (FH). Genetic heterogeneity at this locus raises the possibility that the LDLR may also contribute to variation in cholesterol levels in the normocholesterolemic population. We have determined genotypes at...

Topics

Adult
Cholesterol
DNA
Female
Genetic Variation
Genotype
Haplotypes
Humans
Lipids
Lipoproteins
Male
Models, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Restriction Fragment Length

Receptors, LDL

Source

Identifiers

PMID: 1981179
DOI: 10.1111/j.1399-0004.1990.tb03604.x

Genes

LDLR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1981179-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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