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Article

Detection of influenza A H1N1 and H3N2 mutations conferring resistance to oseltamivir using rolling circle amplification.

Antiviral research - 1 Dec 2009

Steain Megan C, Dwyer Dominic E, Hurt Aeron C, Kol Chenda, Saksena Nitin K, Cunningham Anthony L, Wang Bin

Abstract excerpt

In the event of an influenza pandemic, the use of oseltamivir (OTV) will undoubtedly increase and therefore it is more likely that OTV-resistant influenza strains will also arise. OTV-resistance genotyping using sequence-based testing on viruses isolated in cell culture is time consuming and less likely to detect the low-level presence of drug-resistant virus populations. We have developed a novel rolling circle...

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Source

Identifiers

PMID: 19800370
DOI: 10.1016/j.antiviral.2009.09.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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