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Article

TIRAP Ser180Leu polymorphism is associated with Behcet's disease.

Rheumatology (Oxford, England) - 1 Oct 2011

Durrani Omar, Banahan Katherine, Sheedy Frederick J, McBride Laura, Ben-Chetrit Eldad, Greiner Kathryn, Vaughan Robert W, Kondeatis Elli, Hamburger John, Fortune Farida, Stanford Miles R, Murray Philip I, O'Neill Luke A, Wallace Graham R

Abstract excerpt

OBJECTIVES: The initiating cause of Behçet's disease (BD) is unknown, but an aberrant response to infection has been suggested. In this study, single nucleotide polymorphisms in Toll-like receptors (TLRs) and associated molecules that have a sentinel function at mucosal surfaces were analysed in patients with BD. METHODS: TLR expression was determined by immunohistochemistry in buccal mucosal tissue from patients...

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Source

Identifiers

PMID: 21705416
DOI: 10.1093/rheumatology/ker200

Genes

TIRAP
TLR2
TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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