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Article

Premeiotic disruption of the Neurospora crassa malate synthase gene by native and divergent DNAs.

Molecular & general genetics : MGG - 1 Sept 1990

Connerton I F

Abstract excerpt

Repeat-induced point mutation (RIP) has been used to generate new mutations in the previously uncharacterised gene for malate synthase in Neurospora crassa. Molecular clones carrying the am (NADP-glutamate dehydrogenase) gene and the malate synthase gene from either N. crassa or Aspergillus nidulans have been introduced into Neurospora as ectopic duplicate copies by transformation, selecting for the am+ function...

Topics

Acetates
Blotting, Southern
Cloning, Molecular
DNA, Fungal
Genes, Fungal
Genetic Linkage
Malate Synthase
Mutation
Neurospora crassa
Polymorphism, Restriction Fragment Length
Transformation, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 1979142
DOI: 10.1007/BF00265069

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1979142-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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