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Article

Packaging capacity and stability of human adenovirus type 5 vectors

1 Oct 1993

Abstract excerpt

Adenovirus vectors are extensively used for high-level expression of proteins in mammalian cells and are receiving increasing attention for their potential use as live recombinant vaccines and as transducing viruses for use in gene therapy. Although it is commonly argued that one of the chief advantages of adenovirus vectors is their relative stability, this has not been thoroughly investigated. To examine the...

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PMID: 8371349
DOI: 10.1128/jvi.67.10.5911-5921.1993

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