Article
The sepD5 mutation of Aspergillus nidulans localizes to a gene encoding a LIM domain protein required for contractile ring constriction and recruitment of key septation proteins.
Fungal genetics and biology : FG & B - 1 Jun 2026
Hill Terry W, Page Carson W, Williamson McLean H, Jackson-Hayes Loretta
Abstract excerpt
In this research we localize the cytokinesis-inhibiting sepD5 mutation in Aspergillus nidulans to gene AN3659, previously named paxB, which is predicted to encode a LIM domain protein orthologous to the Pxl1 scaffold proteins of S. cerevisiae and S. pombe. The genetic lesion in sepD5 is predicted to result in a Q-to-R amino acid substitution at position 31 of the 776-residue PaxB protein within a region of...
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